Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LAP3 | P28838 | 4/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28732518 | 0.97 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1LAP3ANPEP | |
| Phosphoric Acid SCHEMBL27757593 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1LAP3ANPEP | |
| SCHEMBL203446 | 0.83 | — | — | |
| SCHEMBL1931944 | 0.83 | — | — | |
| SCHEMBL98317 | 0.83 | — | — | |
| SCHEMBL19066548 | 0.83 | — | — | |
| SCHEMBL5691502 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTDP1CA2 | |
| Phosphoric Acid SCHEMBL27931742 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1CA2MMP1 | |
| Phosphoric Acid SCHEMBL3099518 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1CA2MMP1 | |
| Phosphoric Acid SCHEMBL28671769 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1LAP3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024248312-A1 | POLYOL COMPOSITION FOR PRODUCING RIGID POLYURETHANE FOAM | 롯데케미칼 주식회사 | 2024-12-05 | — | — | WO | disclosed |
| US-20240076436-A1 | POLYURETHANE FOAM COMPOSITION AND USE OF SAME FOR POTTING PRODUCTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-03-07 | — | — | US | disclosed |
| EP-4305084-A1 | POLYURETHANE FOAM COMPOSITION AND USE OF SAME FOR POTTING PRODUCTS | Dow Global Technologies LLC (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-104736761-B | The synthetic leather froth bed being made up of the main chain polyurethane dispersion liquid based on PEPA | 陶氏环球技术有限责任公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104822876-B | The synthetic leather based on polyurethane dispersion liquid comprising acrylic latex | 陶氏环球技术有限责任公司 | 2017-03-08 | — | — | CN | disclosed |
| US-20150299945-A1 | POLYURETHANE DISPERSION BASED SYNTHETIC LEATHERS COMPRISING ACRYLIC LATEX | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150259851-A1 | POLYURETHANE BASED SYNTHETIC LEATHERS COMPRISING NANOPARTICLES AND HAVING IMPROVED PEEL STRENGTH | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-09-17 | — | — | US | disclosed |
| CN-104822876-A | Polyurethane dispersion based synthetic leathers comprising acrylic latex | DOW GLOBAL TECHNOLOGIES INC | 2015-08-05 | — | — | CN | disclosed |
| CN-104736761-A | Synthetic leather foam layer made from polyester polyol based backbone polyurethane dispersion | DOW GLOBAL TECHNOLOGIES INC | 2015-06-24 | — | — | CN | disclosed |
| WO-2014059597-A1 | NANOPARTICLE CONTAINING POLYURETHANE DISPERSIONS AFFORDING MATERIALS HAVING IMPROVED TENSILE STRENGTH AND ELONGATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-1573119-A2 | PROCESS FOR APPLYING A POLYURETHANE DISPERSION BASED FOAM TO AN ARTICLE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004063243-A1 | POLYOL COMPOSITION AND POLYISOCYANATE-BASED FOAM PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-1435366-A1 | Polyol composition and polyisocyanate-based foam prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2004053223-A2 | PROCESS FOR APPLYING A POLYURETHANE DISPERSION BASED FOAM TO AN ARTICLE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040109992-A1 | Process for applying a polyurethane dispersion based foam to an article | GRIBBLE MICHAEL Y (CH) | 2004-06-10 | — | — | US | disclosed |
| US-20040069971-A1 | Polyol compositions and rigid polyisocyanurate foams prepared therefrom | WITTEVEEN MARTIJN M (NL) | 2004-04-15 | — | — | US | disclosed |
| EP-1159341-B1 | POLYURETHANE BASED FOAM CONTAINING EXFOLIATING GRAPHITE AND THE PROCESS FOR THE PREPARATION THEREOF | DOW CHEMICAL CO (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1159341-A1 | POLYURETHANE BASED FOAM CONTAINING EXFOLIATING GRAPHITE AND THE PROCESS FOR THE PREPARATION THEREOF | THE DOW CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000035999-A1 | POLYURETHANE BASED FOAM CONTAINING EXFOLIATING GRAPHITE AND THE PROCESS FOR THE PREPARATION THEREOF | THE DOW CHEMICAL COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |
| US-4659671-A | PHOSPHORYLATION, HYDROLYSIS, AND SEPARATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1987-04-21 | — | — | US | disclosed |