Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	3/20	0.61

▸	TSHR	P16473	2/20	0.61

▸	TDP1	Q9NUW8	2/20	0.33

▸	KDM4E	B2RXH2	1/20	0.32

▸	CYP2C19	P33261	1/20	0.32

▸	KMT2A	Q03164	1/20	0.32

▸	CA2	P00918	1/20	0.31

▸	GGPS1	O95749	2/20	0.31

▸	LMNA	P02545	1/20	0.30

▸	MMP1	P03956	1/20	0.30

▸	MMP2	P08253	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL27931742	1.00	ALDH1A1 (0.61)	ALDH1A1TSHRTDP1KDM4ECYP2C19
Phosphoric Acid SCHEMBL4642670	0.82	ALDH1A1 (0.69)	ALDH1A1TSHRTDP1CA2MMP1
Phosphoric Acid SCHEMBL28732518	0.80	ALDH1A1 (0.65)	ALDH1A1TSHRTDP1CA2MMP1
Propylene Glycol SCHEMBL4585432	0.80	TDP1 (0.59)	ALDH1A1TSHRTDP1CA2GGPS1
Phosphoric Acid SCHEMBL28353739	0.78	LMNA (0.46)	ALDH1A1TDP1KDM4ECYP2C19KMT2A
SCHEMBL203446	0.78	—	—
SCHEMBL5691502	0.78	TSHR (1.00)	ALDH1A1TSHRTDP1KMT2ACA2
SCHEMBL19066548	0.78	—	—
SCHEMBL98317	0.78	—	—
SCHEMBL1931944	0.78	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8293219-B2	Use of long carbon chain quaternary ammonium salt phosphoric acid ester as conditioner for hair	NANJING HUASHI CHEMICAL CO., LTD (CN)	2012-10-23	—	—	US	disclosed
US-20100254931-A1	USE OF LONG CARBON CHAIN QUATERNARY AMMONIUM SALT PHOSPHORIC ACID ESTER AS CONDITIONER FOR HAIR	NANJING ZHONGSHI CHEMICAL CO., LTD. (CN)	2010-10-07	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20100254931-A1	USE OF LONG CARBON CHAIN QUATERNARY AMMONIUM SALT PHOSPHORIC ACID ESTER AS CONDITIONER FOR HAIR	CA2, CA7, CPS1	ALDH1A1 613/4885TSHR 4208/4885TDP1 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.