Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641160 | 0.90 | CYP4F2 (0.58) | LMNAALDH1A1CYP4F2CYP4A11TSHR | |
| SCHEMBL4640477 | 0.84 | LOXL2 (0.60) | ALDH1A1CYP4F2CYP4A11TSHRKDM4E | |
| SCHEMBL3033016 | 0.84 | LMNA (0.66) | LMNAALDH1A1CYP4F2CYP4A11SLC6A2 | |
| SCHEMBL4641021 | 0.83 | TDP1 (0.59) | LMNAALDH1A1SLC6A2TDP1KDM4E | |
| SCHEMBL31575815 | 0.82 | LMNA (0.60) | LMNAALDH1A1SLC6A2TSHRESR1 | |
| SCHEMBL20267329 | 0.82 | LMNA (0.60) | LMNAALDH1A1SLC6A2TSHRESR1 | |
| SCHEMBL15344632 | 0.81 | LMNA (0.62) | LMNAALDH1A1CYP4F2CYP4A11SLC6A2 | |
| SCHEMBL111664 | 0.80 | LMNA (0.75) | LMNAALDH1A1SLC6A2TSHRESR1 | |
| SCHEMBL6527211 | 0.80 | LMNA (0.60) | LMNAALDH1A1CYP4F2CYP4A11SLC6A2 | |
| SCHEMBL31346674 | 0.80 | LMNA (0.60) | LMNAALDH1A1CYP4F2CYP4A11SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120391-B1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6566548-B1 | Alkylene- or phenylene- tetrabenzoic acids and derivatives | NIPPON SODA CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| EP-1120391-A1 | MOLECULAR COMPOUNDS CONTAINING NOVEL CARBOXYLIC ACID DERIVATIVES AS THE CONSTITUENT COMPOUND | NIPPON SODA CO., LTD. (JP) | 2001-08-01 | — | — | EP | disclosed |