SCHEMBL4642859

SCHEMBL4642859

CCCO/[C]=C/c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 1/20 0.36
RELA Q04206 1/20 0.36
BCHE P06276 5/20 0.35
ACHE P22303 5/20 0.35
HPGD P15428 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
CHRNA7 P36544 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642315 0.89 LTA4H (0.43) LMNARELABCHEACHEALDH1A1
SCHEMBL4642411 0.87 LTA4H (0.43) LMNABCHEACHEALDH1A1TP53
SCHEMBL7667578 0.83 RELA (0.42) MEN1KMT2ALMNARELAALDH1A1
SCHEMBL2214717 0.78 MAOB (0.33) MEN1KMT2A
SCHEMBL7759469 0.73 TSHR (0.44) LMNAALDH1A1CYP1A2
SCHEMBL11668109 0.72 CSNK1E (0.38) LMNAALDH1A1
SCHEMBL4232719 0.72 TRPA1 (0.41) MEN1KMT2ALMNARELAHPGD
SCHEMBL4447291 0.72 TRPA1 (0.41) MEN1KMT2ALMNARELAHPGD
SCHEMBL2287959 0.72 TRPA1 (0.41) MEN1KMT2ALMNARELAHPGD
SCHEMBL2455880 0.70 CYP2D6 (0.33) MEN1KMT2AALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1630606-B1 POSITIVE PHOTOSENSITIVE COMPOSITION THINK LABS KK (JP) 2008-08-13 EP disclosed
US-20070212640-A1 Positive Photosensitive Composition THINK LABORATORY CO., LTD. (JP) 2007-09-13 US disclosed
EP-1775632-A1 POSITIVE-WORKING PHOTOSENSITIVE COMPOSITION THINK LABORATORY CO., LTD. (JP) 2007-04-18 EP disclosed
US-20060222998-A1 Positive photosensitive composition THINK LABORATORY CO., LTD. (JP) 2006-10-05 US disclosed
EP-1630606-A1 POSITIVE PHOTOSENSITIVE COMPOSITION THINK LABORATORY CO., LTD. (JP) 2006-03-01 EP disclosed