Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100717 | 0.82 | CCNE1 (0.34) | CCNE1CDK2GSK3B | |
| SCHEMBL5712625 | 0.82 | CHRM2 (0.40) | — | |
| SCHEMBL2781450 | 0.82 | HTT (0.38) | — | |
| SCHEMBL24470470 | 0.80 | — | — | |
| SCHEMBL1799869 | 0.79 | ALDH1A1 (0.46) | GSK3BMAPT | |
| SCHEMBL14063664 | 0.79 | MGLL (0.33) | CCNE1CDK2GSK3B | |
| SCHEMBL12092232 | 0.79 | PSMB8 (0.30) | — | |
| SCHEMBL4393963 | 0.78 | CCNE1 (0.31) | CCNE1CDK2GSK3B | |
| SCHEMBL917159 | 0.78 | ENO1 (0.36) | CCNE1CDK2GSK3B | |
| SCHEMBL3106135 | 0.78 | POLB (0.42) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853084-B1 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| EP-0853084-A2 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |