SCHEMBL4643258

SCHEMBL4643258

C[CH]C(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
ALDH1A1 P00352 6/20 0.54
CYP2A6 P11509 2/20 0.54
ALDH1A3 P47895 1/20 0.48
PARP10 Q53GL7 1/20 0.47
PARP3 Q9Y6F1 1/20 0.47
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH5A1 P51649 1/20 0.43
ABAT P80404 1/20 0.43
STS P08842 1/20 0.42
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.41
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8620443 0.84 KMT2A (0.62) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL8620440 0.84 KMT2A (0.62) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL203500 0.81 KMT2A (0.61) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL14783590 0.80 KMT2A (0.62) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL1665241 0.80 KMT2A (0.53) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL2239275 0.79 KMT2A (0.56) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL4646086 0.79 KMT2A (0.56) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL6243024 0.78 KMT2A (0.60) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL4643342 0.78 ELANE (0.48) KMT2APARP10MAPTKDM4ELMNA
SCHEMBL4644469 0.78 CES2 (0.52) KMT2AALDH1A1CYP2A6PARP10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed