SCHEMBL4643302

SCHEMBL4643302

O=C(CO)Oc1ccc(Br)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LDHA P00338 1/20 0.44
MGLL Q99685 1/20 0.44
POLB P06746 1/20 0.43
MEN1 O00255 3/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
SRD5A2 P31213 1/20 0.42
ESR1 P03372 1/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931453 0.89 KMT2A (0.54) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL1820226 0.84 KMT2A (0.52) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4642216 0.83 KMT2A (0.52) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL1821398 0.81 KMT2A (0.63) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4642695 0.81 KMT2A (0.44) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL5328134 0.81 KMT2A (0.44) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4643998 0.81 MGLL (0.46) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL6865115 0.81 KMT2A (0.44) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4644560 0.80 KMT2A (0.51) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4642156 0.80 KMT2A (0.47) KMT2AMAPTLMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105541597-B A kind of preparation method of 2,4- dihydroxyphenyl acetic acids 中山大学 2018-06-01 CN disclosed
CN-105541597-B A kind of preparation method of 2,4- dihydroxyphenyl acetic acids 中山大学 2018-06-01 CN disclosed
CN-104478837-B A kind of preparation method of 2-arylbenzofuran-3-formic acid compound 中科院广州化学有限公司 2016-06-29 CN disclosed
CN-105646181-A Preparation method of 2-bromine-4-hydroxyphenylacetic acid 中山大学 2016-06-08 CN disclosed
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed