SCHEMBL5328134

SCHEMBL5328134

NCC(=O)Oc1ccc(Br)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MGLL Q99685 1/20 0.42
LDHA P00338 1/20 0.42
MEN1 O00255 3/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
OGG1 O15527 1/20 0.41
ESR1 P03372 1/20 0.40
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820226 0.83 KMT2A (0.52) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4643302 0.81 KMT2A (0.45) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL11773507 0.81 KMT2A (0.45) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL11151702 0.81 KMT2A (0.45) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL561023 0.81 KMT2A (0.45) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL7982673 0.80 KMT2A (0.46) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL2592352 0.79 LMNA (0.57) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL4643998 0.79 MGLL (0.46) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL1821398 0.79 KMT2A (0.63) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL2790323 0.79 KMT2A (0.51) KMT2AMAPTLMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118910628-A Selenizing and amination method of olefin under mild electrochemical condition 湘潭大学 2024-11-08 CN claimed
CN-114644836-A Carboxylate two-photon dye taking fluorene ring as matrix, and synthesis method and application thereof 浙江大学 2022-06-21 CN claimed
CN-102165950-B Bacteriostatic and bactericidal activity of phenylglycine derivative on escherichia coli UNIV ZHEJIANG 2014-02-26 CN claimed
CN-102144992-B Bacteriostatic and bactericidal activity of phenylglycine derivatives to Staphylococcus aureus UNIV ZHEJIANG 2013-04-10 CN claimed
CN-102165950-A Bacteriostatic and bactericidal activity of phenylglycine derivative on escherichia coli UNIV ZHEJIANG 2011-08-31 CN claimed
CN-102144992-A Bacteriostatic and bactericidal activity of phenylglycine derivatives to Staphylococcus aureus UNIV ZHEJIANG 2011-08-10 CN claimed
CN-117362188-B Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2025-05-20 CN disclosed
CN-112672747-B Peptides for activating cell signaling in osteoprogenitor cells 加利福尼亚大学董事会 2025-02-18 CN disclosed
CN-119264419-A Clustering peptide with side group containing functionalized diphenylamine group and preparation method thereof 华东理工大学 2025-01-07 CN disclosed
CN-118910628-A Selenizing and amination method of olefin under mild electrochemical condition 湘潭大学 2024-11-08 CN disclosed
CN-118239850-A Synthesis and application of alpha-alkyl glycine derivative 西北师范大学 2024-06-25 CN disclosed
CN-112939883-B Preparation method of polysubstituted 1, 3-oxazolidine compound 兰州大学 2024-01-16 CN disclosed
CN-117362188-A Synthesis method of alpha-substituted deuterated amino acid ester 广州医科大学 2024-01-09 CN disclosed
CN-102144992-A Bacteriostatic and bactericidal activity of phenylglycine derivatives to Staphylococcus aureus UNIV ZHEJIANG 2011-08-10 CN disclosed
CN-101868469-A Phosphonic acid derivatives and their use as P2Y12ReceptorsAntagonists ACTELION PHARMACEUTICALS LTD 2010-10-20 CN disclosed
CN-100398555-C Protease inhibitors for coronaviruses and SARS-COV and the use thereof CYTOVIA INC (US) 2008-07-02 CN disclosed
WO-2007123686-A2 DPP INHIBITORS AND USES THEREOF POINT THERAPEUTICS, INC. (US) 2007-11-01 WO disclosed
CN-1984909-A Thiazolinone unsubstituted quinolines HOFFMANN LA ROCHE (CH) 2007-06-20 CN disclosed
CN-1784239-A Protease inhibitors of coronavirus and SARS-COV and use thereof CYTOVIA INC (US) 2006-06-07 CN disclosed
CN-1649829-A Novel florfenicol-type antibiotics SCHERING PLOUGH LTD (CH) 2005-08-03 CN disclosed