Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820226 | 0.83 | KMT2A (0.52) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL4643302 | 0.81 | KMT2A (0.45) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL27579730 | 0.81 | KMT2A (0.53) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL27597245 | 0.79 | GAA (0.56) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL27512790 | 0.79 | KMT2A (0.44) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL27483364 | 0.79 | KMT2A (0.44) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL5328134 | 0.79 | KMT2A (0.44) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL4643998 | 0.79 | MGLL (0.46) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL1821398 | 0.79 | KMT2A (0.63) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL28042312 | 0.79 | KMT2A (0.47) | KMT2AMAPTLMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880763-B | A kind of 4-amino-5-replaces-1,2,4-triazole-3-thioketone and preparation method thereof | 陕西科技大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104177350-A | Bitriazole phenyl-substituted oxadiazole compound and preparation method and application thereof | TIANJIN PUMAO TECHNOLOGY DEV CO LTD | 2014-12-03 | — | — | CN | claimed |
| CN-103880763-A | 4-amino-5-substittued-1,2,4-triazole-3-thioketone and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2014-06-25 | — | — | CN | claimed |
| CN-103880763-B | A kind of 4-amino-5-replaces-1,2,4-triazole-3-thioketone and preparation method thereof | 陕西科技大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-103936683-B | A kind of 4-amino-5-replaces-1,2,4-triazole-3-thioketone Schiff and preparation method thereof | 陕西科技大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105001241-A | S-triazolo-thiadiazole and thiadiazine derivatives, preparation method and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-10-28 | — | — | CN | disclosed |
| CN-103724296-B | Piperazine carbonyl derivative that aryl replaces and its preparation method and application | NANJING MEDICAL UNIVERSITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-104177350-A | Bitriazole phenyl-substituted oxadiazole compound and preparation method and application thereof | TIANJIN PUMAO TECHNOLOGY DEV CO LTD | 2014-12-03 | — | — | CN | disclosed |
| CN-103936683-A | 4-amino-5-substituted-1,2,4-triazole-3-thione Schiff base and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2014-07-23 | — | — | CN | disclosed |
| CN-103724296-A | Aryl substituted piperazine carbonyl derivative as well as preparation method and application thereof | UNIV NANJING MEDICAL | 2014-04-16 | — | — | CN | disclosed |
| CN-100443486-C | 7-esterified and 7,20-double esterified camptothecine derivant and method for preparing the same and pharmaceutical combination and uses thereof | INST MATERIA MEDICA CAMS (CN) | 2008-12-17 | — | — | CN | disclosed |
| CN-100417324-C | Compsn. of agricultural pesticide and preparation method | UNIV BEIJING CHEMICAL (CN) | 2008-09-10 | — | — | CN | disclosed |
| CN-1695446-A | Compsn. of agricultural pesticide and preparation method | UNIV BEIJING CHEMICAL (CN) | 2005-11-16 | — | — | CN | disclosed |
| US-6805920-B2 | For producing liquid crystal display (LCD) | NITTO DENKO CORPORATION (JP) | 2004-10-19 | — | — | US | disclosed |
| CN-1482128-A | 7-esterified and 7,20-double esterified camptothecine derivant and method for preparing the same and pharmaceutical combination and uses thereof | 中国医学科学院药物研究所 | 2004-03-17 | — | — | CN | disclosed |
| US-20030072893-A1 | Polymerizable liquid crystal compound and optical film | NITTO DENKO CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| US-4031119-A | LUBRICANTS, GREASES, SEALS | PONOMAREV ALEXEI IVANOVICH | 1977-06-21 | — | — | US | disclosed |