SCHEMBL4643345

SCHEMBL4643345

[CH2]CC(=O)Oc1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ELANE P08246 3/20 0.43
ESR1 P03372 3/20 0.42
MEN1 O00255 1/20 0.42
ESR2 Q92731 1/20 0.42
GAA P10253 2/20 0.42
XBP1 P17861 1/20 0.42
HIF1A Q16665 2/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
CASP6 P55212 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2004570 0.83 KMT2A (0.52) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL689763 0.82 KMT2A (0.54) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL689206 0.82 KMT2A (0.65) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL419283 0.82 KMT2A (0.53) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4642695 0.81 KMT2A (0.44) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL6881808 0.81 KMT2A (0.47) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4644471 0.81 LMNA (0.56) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4642156 0.80 KMT2A (0.47) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL190534 0.80 CYP19A1 (0.52) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL421279 0.79 KMT2A (0.54) KMT2AMAPTALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed