SCHEMBL4644471

SCHEMBL4644471

[CH2]CC(=O)Oc1ccc(OC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
GAA P10253 3/20 0.56
KMT2A Q03164 3/20 0.53
MAPT P10636 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
GSK3B P49841 2/20 0.47
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644295 0.84 KMT2A (0.60) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL5130508 0.83 HTT (0.63) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL8631220 0.83 KMT2A (0.76) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL4642189 0.82 KMT2A (0.58) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL4644246 0.81 CA1 (0.58) LMNAKMT2AMAPTHSD17B10ALDH1A1
SCHEMBL4643749 0.81 LMNA (0.58) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL4643345 0.81 KMT2A (0.45) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL819434 0.81 KMT2A (0.66) LMNAGAAKMT2AMAPTHSD17B10
SCHEMBL4645067 0.80 NQO1 (0.54) LMNAKMT2AALDH1A1TDP1CYP1A2
SCHEMBL4645765 0.79 GAA (0.56) LMNAGAAKMT2AMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed