SCHEMBL689763

SCHEMBL689763

O=C(CC(=O)Oc1ccc(O)cc1)Oc1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
MAPT P10636 3/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
HSD17B10 Q99714 1/20 0.54
GAA P10253 2/20 0.47
BLM P54132 2/20 0.47
GFER P55789 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
THRB P10828 1/20 0.47
CASP6 P55212 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 3/20 0.46
MEN1 O00255 1/20 0.46
ESR2 Q92731 1/20 0.46
ELANE P08246 2/20 0.46
XBP1 P17861 1/20 0.44
HIF1A Q16665 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27998181 0.92 LTA4H (0.54) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL7190278 0.89 MAPT (0.48) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL689206 0.86 KMT2A (0.65) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL9638846 0.84 KMT2A (0.48) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4642156 0.84 KMT2A (0.47) KMT2AMAPTALDH1A1LMNAHTT
Butane SCHEMBL1043355 0.82 KMT2A (0.47) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL689834 0.82 KMT2A (0.43) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL23174851 0.82 KMT2A (0.58) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL4643345 0.82 KMT2A (0.45) KMT2AMAPTALDH1A1LMNAHTT
SCHEMBL561023 0.82 KMT2A (0.45) KMT2AMAPTALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9464183-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2016-10-11 US disclosed
US-8222446-B2 Method for producing dihydroxybenzene derivative MITSUI CHEMICALS, INC. (JP) 2012-07-17 US disclosed
EP-1820667-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2012-02-29 EP disclosed
EP-1724302-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME BRIDGESTONE CORP (JP) 2011-07-20 EP disclosed
US-20110146886-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2011-01-06 US disclosed
EP-2269976-A1 PROCESS FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE Mitsui Chemicals, Inc. (JP) 2011-01-05 EP disclosed
US-7823614-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2010-11-02 US disclosed
US-20090229728-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-09-17 US disclosed
US-20080047650-A1 Rubber Composition And Pneumatic Tire Using The Same BRIDGESTONE CORPORATION (JP) 2008-02-28 US disclosed
EP-1820667-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-22 EP disclosed
EP-1724252-A1 COMPOUND AND COMPOSITION CONTAINING THE SAME Mitsui Chemicals, Inc. (JP) 2006-11-22 EP disclosed
EP-1724302-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME Bridgestone Corporation (JP) 2006-11-22 EP disclosed
US-20060205971-A1 Compound and composition containing the same MITSUI CHEMICALS, INC. (JP) 2006-09-14 US disclosed
US-6586506-B2 Such as a candle, containing wax, oil soluble dye, and a UV-absorbing compound such as propanedioic acid, ((4-methoxyphenyl)methylene), dimethyl ester; discoloration inhibition, longer color shelf life CLARIANT FINANCE (BVI) LIMITED (VG) 2003-07-01 US disclosed
US-20010051680-A1 Colored wax articles CLARIANT FINANCE (BVI) LIMITED (VG) 2001-12-13 US disclosed
EP-1135435-A1 SOLID, SHAPED AND COLORED WAX ARTICLES Clariant Finance (BVI) Limited (VG) 2001-09-26 EP disclosed
US-6262153-B1 Colored wax articles CLARIANT FINANCE (BVI) LIMITED (VG) 2001-07-17 US disclosed
WO-2000022037-A1 SOLID, SHAPED AND COLORED WAX ARTICLES CLARIANT FINANCE (BVI) LIMITED (VG) 2000-04-20 WO disclosed
EP-0061219-A1 p-Hydroxyphenylmalonic acid derivatives and process for their preparation Océ-Andeno B.V. (NL) 1982-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205971-A1 Compound and composition containing the same RFC4, RFC5, RFC1 KMT2A 1603/4885MAPT 1024/4885ALDH1A1 1041/4885
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE UBE2B, UBE2G2, TUBB2B KMT2A 1007/4885MAPT 1366/4885ALDH1A1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.