SCHEMBL4643487

SCHEMBL4643487

O=C(CBr)C(=O)CCCCl

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.38
CES1 P23141 5/20 0.38
TSHR P16473 2/20 0.32
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642219 0.92 CES2 (0.40) CES2CES1TSHR
SCHEMBL4641740 0.83
SCHEMBL4646589 0.78 CES1 (0.41) CES2CES1TSHRALDH1A1TDP1
SCHEMBL27619970 0.77 ALDH1A1 (0.44) CES2CES1TSHRALDH1A1
SCHEMBL9322535 0.76
SCHEMBL4647502 0.76 CAMK2A (0.46) CES2CES1TSHRTRPA1
SCHEMBL31098903 0.75 CES1 (0.36) CES2CES1TSHRALDH1A1TDP1
SCHEMBL4644557 0.74 GPR84 (0.46) CES2CES1TSHRTRPA1
SCHEMBL180158 0.72
SCHEMBL4644763 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed