Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 2/20 | 0.40 |
| ▸ | POR | P16435 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874879 | 0.80 | MAOB (0.40) | ELANEMAOAMAOBKDM4EATM | |
| SCHEMBL22828148 | 0.75 | RAB9A (0.67) | ELANEMAOAMAOBSTK17BKDM4E | |
| SCHEMBL25567546 | 0.75 | ALKBH3 (0.41) | ELANEMAOAMAOBATMHTT | |
| SCHEMBL11460673 | 0.74 | ALDH1A1 (0.38) | ELANEMAOAMAOBSTK17BKDM4E | |
| SCHEMBL182959 | 0.74 | ELANE (0.86) | ELANEMAOAMAOBMETAP1HTT | |
| SCHEMBL583153 | 0.74 | ELANE (0.86) | ELANEMAOAMAOBMETAP1HTT | |
| SCHEMBL31674914 | 0.74 | ELANE (0.77) | ELANEMAOAMAOBMETAP1NQO1 | |
| SCHEMBL4401141 | 0.74 | ELANE (0.77) | ELANEMAOAMAOBMETAP1HTT | |
| SCHEMBL2610165 | 0.74 | ELANE (0.77) | ELANEMAOAMAOBMETAP1NQO1 | |
| SCHEMBL19966838 | 0.74 | GAA (0.50) | ELANEMAOAMAOBKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957455-B1 | METHODS FOR INCREASING THE MEAN PARTICLE SIZE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-05-11 | — | — | EP | disclosed |
| EP-1957455-A2 | METHODS FOR INCREASING THE MEAN PARTICLE SIZE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES | General Electric Company (US) | 2008-08-20 | — | — | EP | disclosed |
| US-7329720-B2 | Methods for increasing the mean particle size of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines | GENERAL ELECTRIC COMPANY (US) | 2008-02-12 | — | — | US | disclosed |
| WO-2007064623-A2 | METHODS FOR INCREASING THE MEAN PARTICLE SIZE OF 2-HYDROCARBYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20070123712-A1 | Methods for increasing the mean particle size of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123712-A1 | Methods for increasing the mean particle size of 2-hydrocarbyl-3,3-bis(hydroxyaryl)phthalimidines | DPYD, PAH, DHFR | ELANE 4042/4885MAOA 1355/4885MAOB 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.