Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645779 | 0.85 | MEN1 (0.46) | MEN1MAPTKMT2APTPN1PTPN11 | |
| SCHEMBL4644818 | 0.83 | CYP3A4 (0.57) | MEN1KMT2ACYP3A4ESR1 | |
| SCHEMBL4645333 | 0.81 | THRB (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL4643582 | 0.80 | PTGS2 (0.39) | MEN1KMT2APTGS2ALDH1A1TSHR | |
| SCHEMBL6247098 | 0.76 | ZDHHC2 (0.48) | MEN1MAPTKMT2ATHRBALDH1A1 | |
| SCHEMBL4642186 | 0.74 | THRB (0.45) | MEN1KMT2ACA1CA2THRB | |
| SCHEMBL4644736 | 0.74 | MEN1 (0.50) | MEN1MAPTKMT2APTPN1PTPN11 | |
| SCHEMBL4644060 | 0.74 | CYP3A4 (0.41) | MAPTKMT2APTPN1BACE1PTGES | |
| SCHEMBL28468806 | 0.73 | BCL9 (0.49) | MEN1MAPTKMT2APTPN1PTPN11 | |
| SCHEMBL4646065 | 0.73 | MGLL (0.49) | MEN1MAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |