SCHEMBL4643791

SCHEMBL4643791

O=C(CCCCl)C(=O)COc1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
GAA P10253 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
FKBP1A P62942 1/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
MAPK1 P28482 1/20 0.42
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
AOC2 O75106 1/20 0.41
DAO P14920 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643318 0.95 NPC1 (0.44) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4641677 0.92 KMT2A (0.47) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4644403 0.87 FKBP1A (0.47) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4641521 0.85 NPC1 (0.44) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4641920 0.84 LMNA (0.49) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4644968 0.83 ALOX15 (0.55) NPC1RAB9AGAASMN1; SMN2HPGD
SCHEMBL4642149 0.83 FKBP1A (0.49) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4643821 0.79 LMNA (0.54) NPC1RAB9ALMNAMAPTGAA
SCHEMBL4644114 0.78 KMT2A (0.56) NPC1RAB9ASMN1; SMN2HPGDALOX15
Potassium Ion SCHEMBL29238217 0.77 NPC1 (0.51) NPC1RAB9ALMNAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed