SCHEMBL4644157

SCHEMBL4644157

O=C(CCCl)Oc1c(Cl)cc(Cl)cc1I

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HIF1A Q16665 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK1 P28482 1/20 0.31
TOP2A P11388 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
ACLY P53396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644138 0.91 MAPT (0.38) LMNAGAACA1CA2CA9
SCHEMBL4641534 0.89 MAPT (0.37) LMNAGAACA1CA2CA9
SCHEMBL4647800 0.89 VCAM1 (0.37) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL4642147 0.88 CA1 (0.37) LMNAGAACA1CA2CA9
SCHEMBL4644524 0.87 ALDH1A1 (0.36) LMNAGAACA1CA2CA9
SCHEMBL4645879 0.86 VCAM1 (0.39) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL4641564 0.86 CA1 (0.32) CA1CA2CA9ALDH1A1KMT2A
SCHEMBL4644511 0.84 VCAM1 (0.40) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL4641943 0.83 KMT2A (0.35) CA1CA2CA9HIF1ACYP1A2
SCHEMBL4645709 0.83 KMT2A (0.34) CA1CA2CA9ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed