SCHEMBL4642147

SCHEMBL4642147

O=C(CCCl)Oc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
HIF1A Q16665 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 4/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TOP2A P11388 1/20 0.34
AKR1C4 P17516 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644157 0.88 LMNA (0.33) CA1CA2CA9LMNAGAA
SCHEMBL4644695 0.87 MAPT (0.41) CA1CA2CA9LMNAGAA
SCHEMBL4642401 0.85 POLB (0.37) LMNAGAAHIF1ACYP1A2CYP2C9
SCHEMBL4642224 0.85 VCAM1 (0.40) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL4642299 0.84 ALDH1A1 (0.41) CA1CA2CA9LMNAGAA
SCHEMBL4643898 0.83 CA1 (0.36) CA1CA2CA9LMNAGAA
SCHEMBL348786 0.82 CA1 (0.41) CA1CA2CA9GAAALDH1A1
SCHEMBL4641868 0.81 VCAM1 (0.43) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL4644419 0.80 VCAM1 (0.44) CA1CA2CA9LMNACYP1A2
SCHEMBL4643664 0.80 MAPT (0.38) CA1CA2CA9ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed