Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021742 | 0.95 | KDM5A (0.43) | CA1CA12CA9KDM5ANPSR1 | |
| Sulfuric Acid SCHEMBL27883459 | 0.92 | CA1 (0.46) | CA1CA12CA9KDM5ANPSR1 | |
| Sulfuric Acid SCHEMBL2148402 | 0.92 | CA1 (0.46) | CA1CA12CA9KDM5ANPSR1 | |
| Sulfuric Acid SCHEMBL5874269 | 0.92 | CA1 (0.46) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL27883468 | 0.90 | KDM5A (0.46) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL13359386 | 0.88 | CA12 (0.40) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL7211715 | 0.88 | APP (0.41) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL14750206 | 0.88 | APP (0.41) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL29774219 | 0.88 | APP (0.41) | CA1CA12CA9KDM5ANPSR1 | |
| SCHEMBL18049426 | 0.88 | CA12 (0.40) | CA1CA12CA9KDM5ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442001-B1 | METHOD FOR ELIMINATING POLARIZABLE IMPURITIES FROM HYDROCARBONS AND HYDROCARBON MIXTURES | MERCK PATENT GMBH (DE) | 2008-08-13 | — | — | EP | disclosed |
| EP-1442001-A2 | METHOD FOR ELIMINATING POLARIZABLE IMPURITIES FROM HYDROCARBONS AND HYDROCARBON MIXTURES | Solvent Innovation GmbH (DE) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037835-A2 | METHOD FOR ELIMINATING POLARIZABLE IMPURITIES FROM HYDROCARBONS WITH IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2003-05-08 | — | — | WO | disclosed |