SCHEMBL4644237

SCHEMBL4644237

CC[CH]C(=O)Oc1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
THRB P10828 2/20 0.43
LTA4H P09960 3/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
BCHE P06276 1/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645333 0.85 THRB (0.45) ELANECA12CA1CA2CA7
SCHEMBL4644289 0.84 KMT2A (0.47) CA12CA1CA2CA7CA9
SCHEMBL4643869 0.82 MGLL (0.47) THRBMEN1KMT2ALMNAMAPK1
SCHEMBL4646732 0.82 NQO1 (0.54) LTA4HMEN1KMT2ALMNACYP1A2
SCHEMBL5612980 0.82 ZDHHC2 (0.46) ELANETHRBKMT2A
SCHEMBL4646086 0.81 KMT2A (0.56) THRBMEN1KMT2ALMNASMN1; SMN2
SCHEMBL4645779 0.80 MEN1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL4641414 0.78 CA1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4643933 0.78 CYP3A4 (0.61) MEN1KMT2ABCHEESR1ESR2
SCHEMBL4643342 0.77 ELANE (0.48) ELANECA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed