SCHEMBL4643869

SCHEMBL4643869

CC[CH]C(=O)Oc1ccc(Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.47
MAPT P10636 4/20 0.43
LMNA P02545 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPK1 P28482 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
RAB9A P51151 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
THRB P10828 3/20 0.42
MAOB P27338 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.40
LDHA P00338 1/20 0.40
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646065 0.85 MGLL (0.49) MGLLMAPTLMNAMEN1KMT2A
SCHEMBL4644289 0.82 KMT2A (0.47) LMNAMEN1KMT2AMAOB
SCHEMBL4644237 0.82 ELANE (0.44) LMNAMEN1KMT2AMAPK1THRB
SCHEMBL4646732 0.81 NQO1 (0.54) LMNAMEN1KMT2ANPSR1MAOB
SCHEMBL5612980 0.80 ZDHHC2 (0.46) MAPTKMT2ARAB9ATHRBL3MBTL1
SCHEMBL4646086 0.79 KMT2A (0.56) MAPTLMNAMEN1KMT2ATHRB
SCHEMBL4642693 0.78 LMNA (0.47) MGLLMAPTLMNAMEN1KMT2A
SCHEMBL9860556 0.77 LDHA (0.47) MGLLMAPTLMNAMEN1KMT2A
SCHEMBL4641414 0.77 CA1 (0.56) MGLLMAPTMEN1KMT2ARAB9A
SCHEMBL28038532 0.77 MGLL (0.44) MGLLMAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed