Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 6/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605327 | 0.75 | ADRB2 (0.45) | ADRB2DNM1KDM4ELMNAHTT | |
| SCHEMBL4644273 | 0.74 | TLR4 (0.53) | ADRB2DNM1KDM4ELMNATLR4 | |
| SCHEMBL4608624 | 0.72 | ADRB2 (0.47) | ADRB2DNM1KDM4ETLR4ADRB3 | |
| SCHEMBL4606845 | 0.68 | ADRB2 (0.42) | ADRB2DNM1KDM4ETLR4GABRP | |
| SCHEMBL1733165 | 0.68 | KMT2A (0.54) | ADRB2DNM1LMNATLR4GABRP | |
| SCHEMBL4608341 | 0.67 | ADRB2 (0.53) | ADRB2DNM1KDM4ELMNATLR4 | |
| SCHEMBL4436284 | 0.67 | ADRB2 (0.55) | ADRB2DNM1KDM4ELMNATLR4 | |
| SCHEMBL9621537 | 0.67 | ADRB2 (0.55) | ADRB2DNM1KDM4ELMNATLR4 | |
| SCHEMBL4605235 | 0.66 | TUBB4A (0.48) | ADRB2DNM1KDM4ELMNATLR4 | |
| SCHEMBL4779938 | 0.66 | ADRB2 (0.51) | ADRB2DNM1KDM4ELMNATLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945612-A2 | HETEROCYCLIC COMPOUNDS AS PSTAT3/IL-6 INHIBITORS | Orchid Research Laboratories Limited (IN) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007042912-A2 | HETEROCYCLIC COMPOUNDS AS PSTAT3/IL-6 INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-19 | — | — | WO | disclosed |