SCHEMBL4644344

SCHEMBL4644344

CCCC[Si](CCCC)(CCCC)OC(=O)CCl

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA14 Q9ULX7 2/20 0.38
FAAH O00519 3/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
ACHE P22303 7/20 0.35
EPHX1 P07099 5/20 0.35
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641471 0.94 FAAH (0.39) CA12CA14FAAHCA2CA7
SCHEMBL4644848 0.92 FAAH (0.42) CA12CA14FAAHCA2CA7
SCHEMBL4642454 0.92 FAAH (0.42) CA12CA14FAAHCA2CA7
SCHEMBL4644941 0.87 ALDH1A1 (0.32) FAAHALDH1A1
SCHEMBL4641905 0.84 FAAH (0.38) CA12CA14FAAHCA2CA7
SCHEMBL4642593 0.82 FAAH (0.40) CA12CA14FAAHCA2CA7
SCHEMBL4645281 0.82 FAAH (0.35) CA12CA14FAAHACHEEPHX1
SCHEMBL4641720 0.81 FAAH (0.42) CA12CA14FAAHALDH1A1
SCHEMBL4644217 0.81 CA12 (0.35) CA12CA14CA2CA7CA9
SCHEMBL4641558 0.79 CA12 (0.34) CA12CA14CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed