SCHEMBL4644848

SCHEMBL4644848

CCCCCCCC[Si](CCCCCCCC)(CCCCCCCC)OC(=O)CCl

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.42
EPHX1 P07099 6/20 0.41
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
NAAA Q02083 1/20 0.38
DGKA P23743 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
CASP2 P42575 1/20 0.37
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642454 1.00 FAAH (0.42) FAAHEPHX1CA12CA14CA2
SCHEMBL4641471 0.98 FAAH (0.39) FAAHEPHX1CA12CA14CA2
SCHEMBL4644344 0.92 CA12 (0.38) FAAHEPHX1CA12CA14CA2
SCHEMBL4642414 0.85 FAAH (0.43) FAAHCA12CA14CA2CA7
SCHEMBL4644124 0.85 FAAH (0.43) FAAHCA12CA14CA2CA7
SCHEMBL4644987 0.84 FAAH (0.45) FAAHCA12CA14CA2CA7
SCHEMBL4643999 0.84 FAAH (0.45) FAAHCA12CA14CA2CA7
SCHEMBL4644941 0.84 ALDH1A1 (0.32) FAAHALDH1A1
SCHEMBL4645878 0.83 FAAH (0.41) FAAHCA12CA14CA2CA7
SCHEMBL4644250 0.82 NAAA (0.39) EPHX1CA12CA14CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed