Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643250 | 0.88 | ALDH1A1 (0.40) | MAPTALDH1A1CYP3A4HCAR2NPC1 | |
| SCHEMBL4645346 | 0.85 | MAPT (0.46) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4645338 | 0.77 | MAPT (0.52) | MAPTLMNAMDM2MDM4ALDH1A1 | |
| SCHEMBL4647206 | 0.77 | MAPT (0.52) | MAPTLMNAMDM2MDM4ALDH1A1 | |
| SCHEMBL4643564 | 0.76 | MAPT (0.43) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4644561 | 0.75 | MAPT (0.48) | MAPTLMNAMDM2MDM4ALDH1A1 | |
| SCHEMBL4647022 | 0.75 | MAPT (0.48) | MAPTLMNAMDM2MDM4ALDH1A1 | |
| SCHEMBL4644572 | 0.73 | MAPT (0.46) | MAPTLMNAMDM2MDM4PTGS2 | |
| SCHEMBL4644973 | 0.72 | CA12 (0.41) | MAPTLMNAALDH1A1CYP3A4NPC1 | |
| Diethyl Maleate SCHEMBL11324124 | 0.72 | MAPT (0.60) | MAPTLMNAMDM2MDM4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |