SCHEMBL4644496

SCHEMBL4644496

c1ccc2c(c1)c1ccccc1n2-c1cc(-n2c3ccccc3c3ccccc32)c2ccc3c(-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)c4ccc1c2c43

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 4/20 0.46
GPR3 P46089 1/20 0.41
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
POLB P06746 1/20 0.39
KIF11 P52732 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP19A1 P11511 1/20 0.34
BACE1 P56817 2/20 0.33
MAPT P10636 4/20 0.33
LMNA P02545 3/20 0.33
HPGD P15428 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PABPC1 P11940 1/20 0.33
HTT P42858 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9921064 0.89 KDM4E (0.39) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL12258331 0.85 KDM4E (0.56) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL12577043 0.83 HSD17B10 (0.42) KDM4EL3MBTL1ATMALDH1A1BACE1
SCHEMBL14066881 0.83 KDM4E (0.45) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL26039067 0.82 HSD17B10 (0.41) KDM4EL3MBTL1ATMALDH1A1CYP1A2
SCHEMBL15945817 0.82 HSD17B10 (0.41) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL27365577 0.81 L3MBTL1 (0.43) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL13899989 0.80 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL13775289 0.79 KDM4E (0.50) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL15945790 0.78 KDM4E (0.45) KDM4EL3MBTL1ATMALDH1A1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10804469-B2 Charge transport material, organic electroluminescent element, and illumination device, display device, or light-emitting device characterized by using said element UDC IRELAND LIMITED (IE) 2020-10-13 US disclosed
US-20150069332-A1 CHARGE TRANSPORT MATERIAL, OGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE, DISPLAY DEVICE, OR LIGHT-EMITTING DEVICE CHARACTERIZED BY USING SAID ELEMENT UDC IRELAND LIMITED (IE) 2015-03-12 US disclosed
US-20150069332-A1 CHARGE TRANSPORT MATERIAL, OGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE, DISPLAY DEVICE, OR LIGHT-EMITTING DEVICE CHARACTERIZED BY USING SAID ELEMENT UDC IRELAND LIMITED (IE) 2015-03-12 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-7989802-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2011-08-02 US disclosed
US-7989802-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2011-08-02 US disclosed
US-20100038634-A1 LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
US-20100038634-A1 LIGHT EMITTING DEVICE MATERIAL AND LIGHT EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2010-02-18 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1345278-B1 Organic electroluminescent element and display FUJIFILM CORP (JP) 2008-08-20 EP disclosed
US-6803126-B2 LIGHT-EMITTING EFFICIENCY, LIGHT-EMITTING LUMINANCE AND COLOR PURITY OF BLUE LIGHT FUJITSU LIMITED (JP) 2004-10-12 US disclosed
US-20030186081-A1 Organic el element and organic el display FUJITSU LIMITED (JP) 2003-10-02 US disclosed
EP-1345278-A2 Organic EL element and organic EL display FUJITSU LIMITED (JP) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 KDM4E 2433/4885L3MBTL1 283/4885ATM 1983/4885
US-10804469-B2 Charge transport material, organic electroluminescent element, and illumination device, display device, or light-emitting device characterized by using said element ITGAL, ITGA1, ITGB1 KDM4E 3242/4885L3MBTL1 250/4885ATM 3137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.