SCHEMBL4644559

SCHEMBL4644559

c1cc(CC2CS2)ccc1CC1CS1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.33
MMP9 P14780 6/20 0.33
MMP14 P50281 6/20 0.33
MMP8 P22894 5/20 0.33
MMP3 P08254 1/20 0.33
MMP7 P09237 1/20 0.33
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CAPN1 P07384 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824285 0.88 CAPN1 (0.46) MMP2MMP9MMP14MMP8MMP3
SCHEMBL4646747 0.86 MMP2 (0.49) MMP2MMP9MMP14MMP8MMP3
SCHEMBL4647523 0.82 MMP2 (0.43) MMP2MMP9MMP14MMP8MMP3
SCHEMBL15282666 0.76 CYP1A2 (0.48) SIGMAR1
SCHEMBL5212421 0.71
SCHEMBL4742114 0.71
SCHEMBL6150876 0.70
SCHEMBL6151277 0.68
SCHEMBL1402882 0.67 CRBN (0.33) LMNA
SCHEMBL1402763 0.67 TSHR (0.37) MMP2MMP9MMP14MMP8MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1962139-A1 Negative resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-08-27 EP disclosed