SCHEMBL4644664

SCHEMBL4644664

CCCCCCC12CCCCC1O2

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.36
EPHX1 P07099 1/20 0.32
CYP1A2 P05177 1/20 0.31
NAAA Q02083 3/20 0.31
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5409238 0.98 SIRT2 (0.33) SIRT2CYP1A2
SCHEMBL6906954 0.93 CYP1A2 (0.33) CYP1A2
SCHEMBL4641169 0.87 CYP1A2 (0.30) CYP1A2
SCHEMBL9488078 0.85
SCHEMBL22470067 0.81 CYP1A2 (0.30) CYP1A2
SCHEMBL9291082 0.78 ALDH1A1 (0.39) EPHX1ALDH1A1
SCHEMBL6062855 0.78
SCHEMBL4438329 0.78 SIGMAR1 (0.31)
SCHEMBL8112711 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL627992 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743353-B2 Additive combinations for lubricants and functional fluids LUBRIZOL CORP (US) 2008-08-06 EP disclosed
EP-0673991-B1 Ashless lubricant LUBRIZOL CORP (US) 2004-06-02 EP disclosed
EP-0769546-B1 Antiwear enhancing composition for lubricants and functional fluids LUBRIZOL CORP (US) 2003-07-30 EP disclosed
EP-0743353-B1 Additive combinations for lubricants and functional fluids LUBRIZOL CORP (US) 2003-01-02 EP disclosed
EP-0787791-B1 Functional fluid compositions having improved frictional and anti-oxidation properties LUBRIZOL CORP (US) 2002-12-18 EP disclosed
EP-0747464-B1 A composition for providing anti-shudder friction durability performance for automatic transmissions LUBRIZOL CORP (US) 2001-07-25 EP disclosed
US-5858929-A CALCIUM SALT OF AN OVERBASED SULFONIC ACID, PHOSPHORIC ACID, THREE FRICTION MODIFIERS, DISUBSTITUTED HYDROGEN PHOSPHITE ANTIWEAR AGENTS, POLYMETHACRYLATE DISPERSANT VISCOSITY MODIFIER OR MALEIC ANHYDRIDE/STYRENE CO-POLYMER, ALKOXYLATED THE LUBRIZOL CORPORATION (US) 1999-01-12 US disclosed
US-5759965-A OVERBASED COMPOUND; AUTOMATIC TRANSMISSION FLUID THE LUBRIZOL CORPORATION (US) 1998-06-02 US disclosed
EP-0787791-A2 Functional fluid compositions having improved frictional and anti-oxidation properties The Lubrizol Corporation (US) 1997-08-06 EP disclosed
EP-0769546-A2 Antiwear enhancing composition for lubricants and functional fluids The Lubrizol Corporation (US) 1997-04-23 EP disclosed
US-5561103-A CONTAINING SELF CONDENSATION PRODUCTS OF ALKYLTHIO ALKANOLS AND DISPERSANTS; LUBRICANTS THE LUBRIZOL CORPORATION (US) 1996-10-01 US disclosed
EP-0673991-A1 Ashless lubricant THE LUBRIZOL CORPORATION (US) 1995-09-27 EP disclosed
EP-0294458-B1 LUBRICANT COMPOSITION The Lubrizol Corporation (US) 1991-08-21 EP disclosed
US-4792410-A MIXTURE OF BORONATED OVERBASED COMPOUND, FRICTION MODIFIER AND OIL THE LUBRIZOL CORPORATION (US) 1988-12-20 US disclosed
EP-0294458-A1 LUBRICANT COMPOSITION. LUBRIZOL CORP (US) 1988-12-14 EP disclosed
WO-1988004684-A1 LUBRICANT COMPOSITION THE LUBRIZOL CORPORATION (US) 1988-06-30 WO disclosed
WO-1987005927-A2 LUBRICANT COMPOSITION THE LUBRIZOL CORPORATION (US) 1987-10-08 WO disclosed
EP-0067002-B1 NOVEL BORON-CONTAINING COMPOSITIONS USEFUL AS LUBRICANT ADDITIVES The Lubrizol Corporation (US) 1987-03-25 EP disclosed
US-4584115-A REACXTION PRODUCT OF BORIC ACID OR TRIOXIDE WITH AN EPOXIDE THE LUBRIZOL CORPORATION (US) 1986-04-22 US disclosed
EP-0067002-A1 Novel boron-containing compositions useful as lubricant additives The Lubrizol Corporation (US) 1982-12-15 EP disclosed