Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | HAAO | P46952 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645833 | 0.82 | TSHR (0.48) | CYP1A2ALDH1A1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL2109549 | 0.74 | ALDH1A1 (0.58) | CYP1A2ALDH1A1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL3367799 | 0.71 | ALDH1A1 (0.43) | CYP1A2ALDH1A1TSHRSMN1; SMN2CASP1 | |
| SCHEMBL27589790 | 0.71 | HAAO (0.38) | CYP1A2ALDH1A1TSHRHAAODAO | |
| Hydrochloric Acid SCHEMBL11858933 | 0.69 | TSHR (0.59) | CYP1A2ALDH1A1TSHRSMN1; SMN2ALOX15 | |
| SCHEMBL19115961 | 0.67 | EPHX2 (0.33) | CYP1A2ALDH1A1TSHRSMN1; SMN2CASP1 | |
| SCHEMBL6236049 | 0.67 | CYP1A2 (0.41) | CYP1A2ALDH1A1TSHRALOX15SELL | |
| SCHEMBL4643432 | 0.67 | CYP1A2 (0.41) | CYP1A2ALDH1A1TSHRSMN1; SMN2CASP1 | |
| SCHEMBL4647359 | 0.67 | ALDH1A1 (0.43) | CYP1A2ALDH1A1ALOX15KDM4EHSD17B10 | |
| SCHEMBL4942021 | 0.66 | CYP1A2 (0.50) | CYP1A2ALDH1A1TSHRSMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443042-B1 | HYBRID ONIUM SALT | WAKO PURE CHEM IND LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7101918-B2 | Hybrid type onium salt | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2006-09-05 | — | — | US | disclosed |
| US-7049464-B2 | Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20050261370-A1 | Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1548002-A1 | PROCESS FOR PRODUCING AMINOALKYLSULFONIC ACID AND METHOD OF SALT EXCHANGE FOR SALT THEREOF | Wako Pure Chemical Industries, Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-20050054677-A1 | Process for preparing amine-substituted benzofurans | KU YI-YIN (US) | 2005-03-10 | — | — | US | disclosed |
| US-20050020710-A1 | Hybrid onium salt | WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| US-6822101-B2 | REACTING 1-(3-BUTYNYL)-PYRROLIDINE OR -PIPERIDINE WITH PHENOLIC COMPOUND; CYCLIZATION; TREATING WITH BORONIC ACID DERIVATIVE; HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES | 2004-11-23 | — | — | US | disclosed |
| EP-1443042-A1 | HYBRID ONIUM SALT | Wako Pure Chemical Industries, Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-20040133007-A1 | Process for preparing amine-substituted benzofurans | ABBOTT LABORATORIES | 2004-07-08 | — | — | US | disclosed |
| WO-2004024707-A2 | PROCESS FOR PREPARING AMINE TYPE SUBSTITUTED BENZOFURANS | ABBOTT LABORATORIES (US) | 2004-03-25 | — | — | WO | disclosed |
| US-20040054185-A1 | Process for preparing amine-substituted benzofurans | COWART MARLON D (US) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261370-A1 | Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof | ARSA, ADSL, ASS1 | CYP1A2 959/4885ALDH1A1 623/4885TSHR 2671/4885 |
| US-20050054677-A1 | Process for preparing amine-substituted benzofurans | HRH4, HRH2, HRH3 | CYP1A2 629/4885ALDH1A1 1468/4885TSHR 915/4885 |
| US-20040133007-A1 | Process for preparing amine-substituted benzofurans | HRH4, HRH2, HRH3 | CYP1A2 578/4885ALDH1A1 1563/4885TSHR 951/4885 |
| US-20040054185-A1 | Process for preparing amine-substituted benzofurans | HRH4, HRH2, HRH3 | CYP1A2 578/4885ALDH1A1 1563/4885TSHR 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.