SCHEMBL4644798

SCHEMBL4644798

CC(=O)C(=O)C(Cl)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.52
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
FFAR2 O15552 1/20 0.42
TSHR P16473 3/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ADRB2 P07550 1/20 0.40
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GABBR2 O75899 3/20 0.38
GABBR1 Q9UBS5 3/20 0.38
LMNA P02545 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP3A4 P08684 1/20 0.38
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3993817 0.83 BRD4 (0.61) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL4642044 0.82 HDAC3 (0.41) HDAC4HDAC7HDAC5TDP1CES2
SCHEMBL15946989 0.81 HPGD (0.47) TSHRMAPK1CES2CES1LMNA
SCHEMBL4647083 0.79 BRD4 (0.52) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL4643994 0.79 TSHR (0.44) TSHRMAPK1TDP1CES2CES1
SCHEMBL497246 0.79 BRD4 (0.43) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL11336506 0.76 BRD4 (0.47) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL2454097 0.76 CYP2C9 (0.47) BRD4HDAC4HDAC7HDAC5TSHR
SCHEMBL5441902 0.74 BRD4 (0.45) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL4507146 0.73 L3MBTL1 (0.50) BRD4HDAC4HDAC7HDAC5FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed