SCHEMBL4647083

SCHEMBL4647083

CC(=O)C(=O)C(O)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.52
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
FFAR2 O15552 1/20 0.42
HPGD P15428 1/20 0.41
TSHR P16473 2/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
ADRB2 P07550 1/20 0.40
AOC3 Q16853 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GABBR2 O75899 3/20 0.38
GABBR1 Q9UBS5 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13170113 0.83 BRD4 (0.61) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL4644798 0.79 BRD4 (0.52) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL4641885 0.79 HDAC3 (0.42) HDAC4HDAC7HDAC5HPGDAOC3
SCHEMBL4646420 0.76 CES2 (0.45) AOC3MEN1KMT2AMAPTCES2
SCHEMBL6366 0.76 LMNA (0.62) BRD4HDAC4HDAC7HDAC5TSHR
SCHEMBL20853599 0.76 BRD4 (0.47) BRD4HDAC4HDAC7HDAC5FFAR2
SCHEMBL29903923 0.76 LMNA (0.62) BRD4HDAC4HDAC7HDAC5TSHR
SCHEMBL6367 0.76 LMNA (0.62) BRD4HDAC4HDAC7HDAC5TSHR
SCHEMBL2163167 0.76 LMNA (0.62) BRD4HDAC4HDAC7HDAC5TSHR
SCHEMBL11836466 0.76 BRD4 (0.47) BRD4HDAC4HDAC7HDAC5FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed