Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26703794 | 0.97 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4644189 | 0.92 | THRB (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL14505099 | 0.90 | THRB (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL12200956 | 0.87 | HTT (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10100417 | 0.86 | THRB (0.51) | TSHRTHRBALDH1A1 | |
| SCHEMBL19856425 | 0.84 | THRB (0.40) | TSHRTHRBALDH1A1POLBCTSK | |
| SCHEMBL156498 | 0.84 | ALDH1A1 (0.42) | TSHRTHRBALDH1A1POLBCTSK | |
| SCHEMBL27932384 | 0.83 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL13882270 | 0.81 | ALDH1A1 (0.42) | TSHRALDH1A1CTSKMEN1KMT2A | |
| SCHEMBL244964 | 0.81 | THRB (0.46) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591098-B1 | Cationically curable composition for dental use | TOKUYAMA CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7365106-B2 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20050250868-A1 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1591098-A1 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2005-11-02 | — | — | EP | disclosed |