Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864892 | 1.00 | CCR5 (0.45) | CCR5LMNAHTR2AHRH1TDP1 | |
| SCHEMBL10349572 | 0.90 | CCR5 (0.41) | CCR5LMNAHTR2AHRH1TDP1 | |
| SCHEMBL3140559 | 0.87 | CYP2D6 (0.42) | HTR2AHRH1TDP1CYP2D6TAAR1 | |
| SCHEMBL1546516 | 0.84 | AOC3 (0.40) | CCR5LMNAHTR2AHRH1TDP1 | |
| SCHEMBL27750548 | 0.83 | CCR5 (0.40) | CCR5LMNACYP2D6TAAR1CTSD | |
| SCHEMBL4994413 | 0.81 | POLB (0.43) | POLB | |
| SCHEMBL1111815 | 0.81 | LMNA (0.45) | CCR5LMNAHTR2AHRH1CYP2D6 | |
| Formamide SCHEMBL28078765 | 0.81 | CCR5 (0.46) | CCR5LMNAHTR2ACYP2D6TAAR1 | |
| SCHEMBL12309826 | 0.80 | ADRA2A (0.38) | LMNATDP1MEN1KMT2ACASP1 | |
| SCHEMBL6013632 | 0.80 | CCR5 (0.42) | CCR5LMNACYP2D6TAAR1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288669-A | Atrolactic acid amide derivative and applications thereof | UNIV NANKAI | 2013-09-11 | — | — | CN | claimed |
| US-20180305404-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | ALPHABETA AB (SE) | 2018-10-25 | — | — | US | disclosed |
| US-10023610-B2 | Ligands for prevention of neurotoxicity of the alzheimer's disease related amyloid-beta peptide | ALPHABETA AB (SE) | 2018-07-17 | — | — | US | disclosed |
| EP-1941870-B1 | Perfume Composition comprising perilla aldehyde | SHISEIDO CO LTD (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-3166579-A1 | COMPACT OR FREE ANHYDROUS POWDER BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT | L'Oréal (FR) | 2017-05-17 | — | — | EP | disclosed |
| EP-2852573-B1 | N-[3-(2-CARBOXYETHYL)PHENYL]-PIPERIDIN-1-YL ACETAMIDE DERIVATIVES AND THEIR USE AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma AG (DE) | 2017-02-01 | — | — | EP | disclosed |
| US-20160340387-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | ALPHABETA AB (SE) | 2016-11-24 | — | — | US | disclosed |
| EP-3094641-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | Alphabeta AB (SE) | 2016-11-23 | — | — | EP | disclosed |
| WO-2016005248-A1 | COMPACT OR FREE ANHYDROUS POWDER BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT | L'OREAL (FR) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015107170-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | ALPHABETA AB (SE) | 2015-07-23 | — | — | WO | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4774076-A | DENTIFRICES, MOUTHWASHES | LION CORPORATION (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4649044-A | DISCOLORATION INHIBITION | LION CORPORATION (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4584128-A | Mixture of one or more t-mercapto terpene isomers and α-terpineol organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-04-22 | — | — | US | disclosed |
| US-4481221-A | NORPINANE OR NORBORNANE RING | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-11-06 | — | — | US | disclosed |
| US-4465695-A | FLAVOR, AROMA ENHANCERS FOR FOODS, VITAMINS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023610-B2 | Ligands for prevention of neurotoxicity of the alzheimer's disease related amyloid-beta peptide | APP, BACE1, PSEN1 | CCR5 2520/4885LMNA 1734/4885HTR2A 1731/4885 |
| US-20160340387-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | APP, BACE1, PSEN1 | CCR5 2754/4885LMNA 2042/4885HTR2A 1943/4885 |
| US-20180305404-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | APP, BACE1, PSEN1 | CCR5 2754/4885LMNA 2042/4885HTR2A 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.