Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648222 | 0.89 | MEN1 (0.35) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4648538 | 0.89 | HTR3E (0.32) | MAPTALDH1A1LMNANPSR1HTR3E | |
| SCHEMBL4648584 | 0.84 | MAPT (0.34) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4647179 | 0.80 | NOS3 (0.34) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4646104 | 0.80 | MAPT (0.50) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4647027 | 0.78 | MAPT (0.46) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4647939 | 0.78 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4645596 | 0.77 | MAPT (0.54) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4649018 | 0.76 | MAPT (0.35) | MEN1MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL4648050 | 0.76 | HDAC3 (0.35) | MEN1MAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |