Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.61 |
| ▸ | MMP2 | P08253 | 4/20 | 0.61 |
| ▸ | MMP9 | P14780 | 4/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648657 | 0.82 | EGFR (0.47) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL4646176 | 0.81 | EGFR (0.62) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL4645874 | 0.79 | ALDH1A1 (0.57) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL30764101 | 0.79 | MMP1 (0.71) | MMP1MMP2MMP9EGFRTRPA1 | |
| SCHEMBL7814579 | 0.79 | MMP1 (0.71) | MMP1MMP2MMP9EGFRTRPA1 | |
| SCHEMBL7814581 | 0.79 | MMP1 (0.71) | MMP1MMP2MMP9EGFRTRPA1 | |
| SCHEMBL4646819 | 0.78 | MAPT (0.54) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL31116894 | 0.78 | MMP1 (0.56) | MMP1MMP2MMP9EGFRNPC1 | |
| N-(2-Chlorophenyl)Cinnamamide SCHEMBL3063601 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9EGFRNPC1 | |
| N-(2-Chlorophenyl)Cinnamamide SCHEMBL9988230 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9EGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |