Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | MMP2 | P08253 | 4/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648657 | 0.87 | EGFR (0.47) | EGFRKMT2AMAPTMEN1RAB9A | |
| SCHEMBL4645874 | 0.84 | ALDH1A1 (0.57) | EGFRMAPTRAB9ANPSR1MMP1 | |
| SCHEMBL4646819 | 0.83 | MAPT (0.54) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL4647415 | 0.82 | HIF1A (0.47) | EGFRKMT2AMAPTMEN1MMP1 | |
| SCHEMBL4645554 | 0.81 | MMP1 (0.61) | EGFRKMT2AMAPTMEN1RAB9A | |
| SCHEMBL4646853 | 0.78 | MGLL (0.55) | KMT2AMAPTMEN1MMP1MMP2 | |
| SCHEMBL4648924 | 0.78 | ALDH1A1 (0.58) | EGFRKMT2AMAPTMEN1RAB9A | |
| SCHEMBL4648316 | 0.78 | MMP1 (0.61) | EGFRKMT2AMAPTMEN1RAB9A | |
| SCHEMBL4645027 | 0.78 | MMP1 (0.61) | EGFRKMT2AMAPTMEN1RAB9A | |
| SCHEMBL4644760 | 0.78 | ALDH1A1 (0.54) | EGFRKMT2AMAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |