Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648577 | 0.84 | BCHE (0.36) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4645225 | 0.82 | NOS3 (0.37) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4647489 | 0.81 | CYP2D6 (0.39) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4648222 | 0.77 | MEN1 (0.35) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4647260 | 0.76 | BCHE (0.39) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL4647590 | 0.76 | ACHE (0.39) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4646608 | 0.74 | ACHE (0.41) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4646168 | 0.74 | HPGD (0.34) | MAPTMETAP2HPGD | |
| SCHEMBL4646104 | 0.73 | MAPT (0.50) | SMN1; SMN2NOS3NOS1NOS2MAPT | |
| SCHEMBL4647027 | 0.71 | MAPT (0.46) | SMN1; SMN2NOS3NOS1NOS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |