Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648577 | 0.94 | BCHE (0.36) | CYP2D6HIF1ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4645225 | 0.93 | NOS3 (0.37) | CYP2D6IDO1LMNAALDH1A1HPGD | |
| SCHEMBL4647260 | 0.86 | BCHE (0.39) | IDO1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL4647590 | 0.86 | ACHE (0.39) | CYP1A2CYP3A4CYP2C19IDO1LMNA | |
| SCHEMBL4647900 | 0.86 | EPHX1 (0.35) | CYP2D6CYP1A2CYP3A4CYP2C19IDO1 | |
| SCHEMBL4646174 | 0.86 | KMT2A (0.39) | CYP2D6CYP1A2CYP3A4CYP2C19IDO1 | |
| SCHEMBL4646608 | 0.84 | ACHE (0.41) | IDO1ALDH1A1BCHEACHESMN1; SMN2 | |
| SCHEMBL4645967 | 0.81 | SMN1; SMN2 (0.34) | CYP2D6HIF1ALMNAALDH1A1HPGD | |
| SCHEMBL4645596 | 0.78 | MAPT (0.54) | CYP2D6HIF1ACYP3A4LMNAALDH1A1 | |
| SCHEMBL4646104 | 0.75 | MAPT (0.50) | CYP2D6HIF1ACYP3A4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |