SCHEMBL4646381

SCHEMBL4646381

Cc1ccc([I+]c2ccc(Sc3ccc([S+](c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
NPSR1 Q6W5P4 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HKDC1 Q2TB90 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MLYCD O95822 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 2/20 0.33
ADRB2 P07550 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641462 0.91 ALDH1A1 (0.37) ALDH1A1HPGDTSHRCYP3A4
SCHEMBL4641917 0.90 ALDH1A1 (0.36) ALDH1A1HPGD
SCHEMBL686333 0.89 MAPT (0.44) MAPTNPSR1MEN1KMT2AHKDC1
SCHEMBL685966 0.89 MAPT (0.44) MAPTNPSR1MEN1KMT2AHKDC1
SCHEMBL685986 0.89 MAPT (0.44) MAPTNPSR1MEN1KMT2AHKDC1
SCHEMBL686336 0.88 ALDH1A1 (0.46) MAPTNPSR1MEN1KMT2AHKDC1
Perchlorate SCHEMBL4647394 0.87 MLYCD (0.33) MAPTNPSR1MEN1KMT2AHKDC1
SCHEMBL685341 0.86 ALDH1A1 (0.47) MAPTNPSR1MEN1KMT2AHKDC1
Perchlorate SCHEMBL4643320 0.85 ALDH1A1 (0.33) ALDH1A1HPGD
Perchlorate SCHEMBL4644301 0.83 ALDH1A1 (0.33) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed