SCHEMBL4646495

SCHEMBL4646495

COc1c2ccccc2c(OC)c2c1ccc1cccc(C)c12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 2/20 0.52
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HPGD P15428 4/20 0.44
HSD17B10 Q99714 4/20 0.44
TSHR P16473 3/20 0.44
CYP3A4 P08684 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP2A6 P11509 4/20 0.44
POLB P06746 1/20 0.43
CYP1A2 P05177 6/20 0.41
THRB P10828 1/20 0.41
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334760 0.87 ALDH1A1 (0.62) ALDH1A1MAPK1KDM4ESMN1; SMN2HPGD
SCHEMBL16335901 0.82 ALDH1A1 (0.56) ALDH1A1MAPK1KDM4ESMN1; SMN2HPGD
SCHEMBL30661083 0.80 ALDH1A1 (0.62) ALDH1A1MAPK1KDM4ESMN1; SMN2HPGD
SCHEMBL1618726 0.77 ALDH1A1 (0.58) ALDH1A1MAPK1KDM4ESMN1; SMN2HPGD
SCHEMBL597308 0.75 ALDH1A1 (0.62) ALDH1A1MAPK1HPGDHSD17B10TSHR
SCHEMBL4647758 0.74 CYP1A2 (0.59) ALDH1A1MAPK1KDM4EHPGDHSD17B10
SCHEMBL7218459 0.74 ALDH1A1 (0.55) ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10
SCHEMBL27878512 0.73 ALDH1A1 (0.65) ALDH1A1MAPK1HPGDHSD17B10TSHR
SCHEMBL550683 0.73 ALDH1A1 (0.65) ALDH1A1MAPK1HPGDHSD17B10TSHR
SCHEMBL10022717 0.73 ALDH1A1 (0.71) ALDH1A1MAPK1KDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-4091578-A1 METHOD FOR PRODUCING PLATE DENTURE, CURABLE STEREOLITHOGRAPHIC COMPOSITION, AND PLATE DENTURE PRODUCTION KIT Tokuyama Dental Corporation (JP) 2022-11-23 EP disclosed
EP-1591098-B1 Cationically curable composition for dental use TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-7365106-B2 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2008-04-29 US disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
CN-1732883-A Cationically curable composition for dental use TOKUYAMA CORP (JP) 2006-02-15 CN disclosed
US-20050250868-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-10 US disclosed
EP-1591098-A1 Cationically curable composition for dental use TOKUYAMA CORPORATION (JP) 2005-11-02 EP disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed