SCHEMBL4646506

SCHEMBL4646506

O=C(CCO)C(=O)COc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.59
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
ALPL P05186 1/20 0.51
ALPI P09923 1/20 0.51
ALPG P10696 1/20 0.51
ALDH1A1 P00352 3/20 0.50
RECQL P46063 1/20 0.50
HPGD P15428 1/20 0.46
GAA P10253 2/20 0.45
USP2 O75604 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
FFAR1 O14842 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
MAPT P10636 1/20 0.43
PTPN7 P35236 1/20 0.43
PTPN12 Q05209 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4744536 0.89 ALOX15 (0.55) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644549 0.87 KMT2A (0.56) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644360 0.84 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644307 0.83 ALOX15 (0.57) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4642149 0.81 FKBP1A (0.49) KMT2AMEN1ALDH1A1GAASMN1; SMN2
SCHEMBL4644968 0.81 ALOX15 (0.55) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644114 0.80 KMT2A (0.56) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL6906212 0.79 ALOX15 (0.68) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4643662 0.78 ALOX15 (0.61) ALOX15KMT2AMEN1ALPLALPI
Ethylene Glycol SCHEMBL27812415 0.78 ALOX15 (0.87) ALOX15KMT2AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed