SCHEMBL4744536

SCHEMBL4744536

O=C(CCCO)C(=O)COc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.55
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
ALPL P05186 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
ALDH1A1 P00352 1/20 0.47
RECQL P46063 1/20 0.47
HDAC1 Q13547 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644549 0.95 KMT2A (0.56) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4646506 0.89 ALOX15 (0.59) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644968 0.86 ALOX15 (0.55) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644114 0.84 KMT2A (0.56) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644403 0.83 FKBP1A (0.47) KMT2AMEN1ALDH1A1GAASMN1; SMN2
SCHEMBL4644360 0.81 ALOX15 (0.63) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL4644307 0.80 ALOX15 (0.57) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL6906212 0.77 ALOX15 (0.68) ALOX15KMT2AMEN1ALPLALPI
SCHEMBL27620092 0.76 GRM5 (0.46) KMT2AALDH1A1
SCHEMBL4643662 0.76 ALOX15 (0.61) ALOX15KMT2AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed