Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.56 |
| ▸ | FAP | Q12884 | 6/20 | 0.56 |
| ▸ | DPP4 | P27487 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578875 | 0.88 | PREP (0.46) | PREPFAPDPP4CYP3A4CYP2C9 | |
| SCHEMBL464681 | 0.87 | PREP (0.55) | PREPFAPDPP4NPSR1F2 | |
| SCHEMBL29985759 | 0.86 | PREP (0.44) | PREPFAPDPP4CYP3A4CYP2C9 | |
| SCHEMBL28913603 | 0.85 | FAP (0.61) | PREPFAPDPP4CYP2C19ACE | |
| SCHEMBL30439075 | 0.85 | P2RX7 (0.49) | CYP3A4CYP2C9PKMCYP2C19ACE | |
| SCHEMBL26391683 | 0.85 | PREP (0.59) | PREPFAPDPP4CYP3A4CYP2C9 | |
| SCHEMBL1509677 | 0.83 | DPP4 (0.54) | PREPFAPDPP4CYP2C19SMN1; SMN2 | |
| SCHEMBL17202450 | 0.83 | ACE (0.49) | PREPFAPDPP4CYP2C19ACE | |
| SCHEMBL13012657 | 0.83 | FAP (0.56) | PREPFAPDPP4ACEF2 | |
| SCHEMBL8564779 | 0.82 | DPP4 (0.46) | PREPFAPDPP4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |