Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648115 | 0.85 | HIF1A (0.51) | EGFRMEN1KMT2AMMP1MMP2 | |
| SCHEMBL4645874 | 0.85 | ALDH1A1 (0.57) | EGFRRAB9ANPC1ALDH1A1MMP1 | |
| SCHEMBL4645027 | 0.84 | MMP1 (0.61) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4646849 | 0.83 | MMP1 (0.68) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4647079 | 0.82 | MAPT (0.54) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4647932 | 0.82 | MAPT (0.54) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4648316 | 0.81 | MMP1 (0.61) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4644760 | 0.81 | ALDH1A1 (0.54) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4648924 | 0.81 | ALDH1A1 (0.58) | EGFRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL4649146 | 0.81 | ALDH1A1 (0.62) | EGFRRAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |