Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646880 | 0.85 | EGFR (0.64) | MMP1MMP2MMP9EGFRLPAR1 | |
| SCHEMBL4646053 | 0.83 | MMP1 (0.71) | HIF1ATRPV1MMP1MMP2MMP9 | |
| SCHEMBL4648540 | 0.83 | MMP1 (0.64) | HIF1AMMP1MMP2MMP9EGFR | |
| SCHEMBL4645874 | 0.82 | ALDH1A1 (0.57) | HIF1AMMP1MMP2MMP9EGFR | |
| SCHEMBL4646853 | 0.81 | MGLL (0.55) | HIF1AMMP1MMP2MMP9LPAR1 | |
| SCHEMBL11099426 | 0.81 | LPAR2 (0.71) | TRPV1FADS1EGFRLPAR1LPAR2 | |
| SCHEMBL4646819 | 0.77 | MAPT (0.54) | HIF1ATRPV1CA2MEN1KMT2A | |
| SCHEMBL4647915 | 0.77 | SMN1; SMN2 (0.56) | HIF1AMMP1MMP2MMP9MEN1 | |
| SCHEMBL4647415 | 0.77 | HIF1A (0.47) | HIF1AMMP1MMP2MMP9EGFR | |
| SCHEMBL1013517 | 0.77 | CYP1A2 (0.65) | FADS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |