SCHEMBL4647372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4646409	0.91	MEN1 (0.47)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL4687933	0.91	MEN1 (0.47)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL14025310	0.87	MEN1 (0.43)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL4646869	0.82	NEK1 (0.47)	MEN1KMT2ANEK1POLBMMP2
	SCHEMBL14025315	0.80	NEK1 (0.55)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL4647511	0.80	NEK1 (0.52)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL4648410	0.79	NEK1 (0.56)	MEN1KMT2AMMP7NEK1POLB
	SCHEMBL4648789	0.72	NR3C1 (0.49)	MEN1KMT2ANEK1POLBMMP2
	SCHEMBL4685322	0.72	NR3C1 (0.47)	MEN1KMT2ANEK1POLBMMP2
	SCHEMBL4647690	0.72	NR3C1 (0.47)	MEN1KMT2ANEK1POLBMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.