Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993694 | 0.86 | L3MBTL1 (0.34) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL16592816 | 0.85 | MAOA (0.35) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL43804 | 0.84 | L3MBTL1 (0.60) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL44713 | 0.83 | ALDH1A1 (0.42) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL43906 | 0.82 | AAK1 (0.46) | L3MBTL1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL16592883 | 0.82 | L3MBTL1 (0.39) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL44476 | 0.81 | GAA (0.37) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL44282 | 0.81 | PPARA (0.41) | L3MBTL1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13844881 | 0.81 | L3MBTL1 (0.40) | L3MBTL1RAB9ANPC1TP53MAPT | |
| SCHEMBL44465 | 0.81 | MAPK1 (0.45) | L3MBTL1RAB9ANPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |