SCHEMBL4647645

SCHEMBL4647645

Nc1nccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.46
USP7 Q93009 2/20 0.43
PRKACA P17612 2/20 0.42
TDO2 P48775 1/20 0.42
SMARCA2 P51531 1/20 0.42
SMARCA4 P51532 1/20 0.42
PBRM1 Q86U86 1/20 0.42
ASIC3 Q9UHC3 1/20 0.42
AURKA O14965 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ADORA2A P29274 1/20 0.42
MAP4K4 O95819 2/20 0.42
IKBKB O14920 1/20 0.42
CHUK O15111 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
PAK4 O96013 1/20 0.42
CSF1R P07333 1/20 0.42
RET P07949 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360194 1.00 GSK3B (0.46) GSK3BUSP7PRKACATDO2SMARCA2
SCHEMBL1165179 0.81 GSK3B (0.47) GSK3BUSP7PRKACATDO2SMARCA2
SCHEMBL19462191 0.81 PRKACA (0.44) USP7PRKACATDO2ASIC3AURKA
SCHEMBL15865506 0.79 NOS2 (0.54) USP7PRKACATDO2ASIC3AURKA
SCHEMBL15865503 0.79 NOS3 (0.54) GSK3BPRKACATDO2SMARCA2SMARCA4
SCHEMBL28175819 0.78 GSK3B (0.45) GSK3BUSP7PRKACATDO2SMARCA2
SCHEMBL16196251 0.78 USP7 (0.42) GSK3BUSP7PRKACASMARCA2SMARCA4
SCHEMBL28145719 0.78 ADORA2A (0.41) PRKACAASIC3AURKAHSP90AA1ADORA2A
SCHEMBL996432 0.77 CCNA2 (0.45) GSK3BPRKACATDO2ADORA2AMAP4K4
SCHEMBL2489243 0.77 LRRK2 (0.43) GSK3BPRKACATDO2ADORA2AMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459730-A Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-08-09 CN claimed
CN-111094385-B Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-04-09 CN claimed
CN-118459730-A Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-08-09 CN disclosed
CN-111094385-B Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2024-04-09 CN disclosed
CN-111094385-A Charge-transporting compound, composition containing charge-transporting compound, and organic electroluminescent element using same 三菱化学株式会社 2020-05-01 CN disclosed
EP-0977088-B1 Use of an electrophotographic photosensitive member for an electrophotographic apparatus equipped with a semiconductor laser having wavelengths from 380nm to 500nm, and electrophotographic apparatus CANON KK (JP) 2008-08-20 EP disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 US disclosed
EP-1536292-A2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2005-06-01 EP disclosed
US-20050111880-A1 Electrophotographic photosensitive member, a charging means, a semiconductor laser as an exposure means, a developing means, a transfer means and a light-emitting diode as a destaticizing means for the electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2005-05-26 US disclosed
US-6641974-B2 Copolymer KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2003-11-04 US disclosed
US-20010041302-A1 Chemically amplified resist composition containing low molecular weight additives SK MATERIALS PERFORMANCE CO., LTD. (KR) 2001-11-15 US disclosed
EP-1126320-A2 Chemically amplified resist composition containing low molecular weight additives Korea Kumho Petrochemical Co. Ltd. (KR) 2001-08-22 EP disclosed
US-6183922-B1 FOR IMAGES HIGH RESOLUTION CANON KABUSHIKI KAISHA (JP) 2001-02-06 US disclosed
EP-0977088-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2000-02-02 EP disclosed
EP-0356993-B1 Image forming method CANON KK (JP) 1995-11-02 EP disclosed
US-4999272-A Electrostatic images CANON KABUSHIKI KAISHA (JP) 1991-03-12 US disclosed
EP-0356993-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1990-03-07 EP disclosed
US-3965100-A 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed