SCHEMBL4647693

SCHEMBL4647693

CC(C)(C)[Si](OC(=O)CCCCO)(C(C)(C)C)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
VCAM1 P19320 2/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP4F2 P78329 3/20 0.34
CYP4A11 Q02928 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
DGKA P23743 1/20 0.31
RECQL P46063 1/20 0.31
GAA P10253 1/20 0.31
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641490 0.94 CAMK2A (0.36) VCAM1CYP4F2CYP4A11TDP1TSHR
SCHEMBL4643987 0.85 VCAM1 (0.31) VCAM1
SCHEMBL4643796 0.82 TSHR (0.32) TSHRDGKARECQL
SCHEMBL4641897 0.80 TSHR (0.33) TSHR
SCHEMBL4642086 0.80 TSHR (0.33) KDM4ETSHR
SCHEMBL4643892 0.77 GPR84 (0.41) GPR84FFAR1FFAR4VCAM1KDM4E
SCHEMBL4643849 0.76
SCHEMBL4644982 0.75
SCHEMBL4646963 0.75
SCHEMBL4642065 0.73 KDM4E (0.41) GPR84FFAR1FFAR4KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed