SCHEMBL4643796

SCHEMBL4643796

CC(C)(C)[Si](OC(=O)CCCCCl)(C(C)(C)C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
DGKA P23743 1/20 0.31
RECQL P46063 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642086 0.94 TSHR (0.33) TSHR
SCHEMBL4644982 0.86
SCHEMBL4647693 0.82 GPR84 (0.37) TSHRDGKARECQL
SCHEMBL4641490 0.80 CAMK2A (0.36) TSHR
SCHEMBL4641897 0.78 TSHR (0.33) TSHR
SCHEMBL4645583 0.78 TSHR (0.36) TSHRDGKAFAAH
SCHEMBL4645372 0.77
SCHEMBL4643987 0.75 VCAM1 (0.31)
SCHEMBL4647045 0.74 DGKA (0.35) TSHRDGKAFAAH
SCHEMBL4576643 0.74 EPHX2 (0.41) TSHRDGKARECQLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed